Pr David Laharie

Biographie

Formation et expérience

David Laharie est Professeur Hépato-gastroentérologie à l’Université de Bordeaux et chef de service au CHU de Bordeaux. 

Travaux et sociétés savantes

Il est vice-président du Groupe d’Étude Thérapeutique des Affections Inflammatoires du Tube Digestif (GETAID) et Secrétaire adjoint aux Relations internationales de la Société Nationale Française de Gastro-Entérologie (SNFGE).

Publications

Laharie D, Debeugny S, Peeters M, Van Gossum A, Gower-Rousseau C, Bélaiche J, Fiasse R, Dupas JL, Lerebours E, Piotte S, Cortot A, Vermeire S, Grandbastien B, Colombel JF. Inflammatory bowel disease in spouses and their offspring. Gastroenterology 2001 ; 120 : 816-9.

Laharie D, Zerbib F, Adhoute X, Boué-Lahorgue X, Foucher J, Castera L, Rullier A, Bertet J, Couzigou P, Amouretti M, de Lédinghen V. Diagnosis of.liver fibrosis by transient elastrography (FibroScan) and noninvasive methods in Crohn's disease patients treated with methotrexate. Aliment Pharmacol Ther 2006; 23: 1621-8.

Laharie D, Menard S, Asencio C, Vidal-Martinez T, Rullier A, Zerbib F, Candalh C, Mégraud F, Heyman M, Matysiak-Budnik T. Effect of Rebamipide on the Colonic Barrier in Interleukin-10-Deficient Mice. Dig Dis Sci 2007; 52: 84-92.

Laharie D, Chanteloup E, El Hanafi K, Subtil C, de Lédinghen V. Tolerance and efficacy of a postponed retreatment with infliximab in Crohn's disease. Aliment Pharmacol Ther 2009; 29: 1240-8.

Varon C, Duriez A, Lehours P, Ménard A, Layé S, Zerbib F, Mégraud F, Laharie D. Study of Helicobacter pullorum proinflammatory properties on human epithelial cells in vitro. Gut 2009; 58: 629-35.

Laharie D, Asencio C, Asselineau J, Bulois P, Bourreille A, Moreau J, Bonjean P, Lamarque D, Pariente A, Soulé JC, Charachon A, Coffin B, Perez P, Mégraud F, Zerbib F. Association between entero-hepatic Helicobacter species and Crohn's disease: a prospective cross-sectional study. Aliment Pharm Ther 2009; 30: 283-93.

Laharie D, Seneschal J, Schaeverbeke T, Doutre MS, Longy-Boursier M, Pellegrin JL, Chabrun E, Villars S, Zerbib F, de Lédinghen V. Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: A case-control study. J Hepatol. 2010; 53: 1035-40.

Roumeguere P, Bouchard D, Pigot F, Castinel A, Juguet F, Gaye D, Capdepont M, Zerbib F, Laharie D.

Combined approach with infliximab, surgery, and methotrexate in severe fistulizing anoperineal Crohnf s disease: Results from a prospective study. Inflamm Bowel Dis 2011; 17: 69-76.

Laharie D, Reffet A, Belleannée G, Chabrun E, Subtil C, Razaire S, Capdepont M, de Lédinghen V. Mucosal healing with methotrexate in Crohnls disease: a prospective comparative study with azathioprine and infliximab. Aliment Pharmacol Ther. 2011; 33:714-21.

Laharie D, Bourreille A, Branche J, Allez M, Bouhnik Y, Filippi J, Zerbib F, Savoye G, Nachury M, Moreau J, Delchier JC, Cosnes J, Rican E, Dewit O, Lopez-Sanroman A, Dupas JL, Carbonnel F, Bommelaer G, Coffin B, Roblin X, Van Assche G, Esteve M, Färkkilä M, Gisbert JP, Marteau P, Nahon S, de Vos M, Franchimont D, Mary JY, Colombel JF, Lémann M; for the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives. Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial. Lancet 2012.